The Human Foundation Model for CNS Drug Development

We extract multimodal signatures from neuro-immune brain organoids, align them to large-scale human datasets, and build AI models that help pharma predict which compounds will work — in humans, before the clinic.

Neuro-immune organoids → Multimodal disease signatures → Human-anchored AI → Clinical prediction

Why This Matters

CNS drug development has the highest failure rate in medicine — and the root cause is a data problem. Preclinical models don't capture human neuro-immune biology, so compounds that look promising in the lab routinely collapse in trials. The field has been flying blind, optimizing for the wrong biology in the wrong species. What's been missing is a system that generates human-relevant disease signatures and validates them against real patient data — before a single dollar is spent in the clinic.

>95% CNS drug candidate failure rate in clinical trials
$2B+ Average cost to bring a CNS drug to market
10–15 yrs Typical development timeline before patient access

Our Discovery Engine

I

Neuro-Immune Brain Organoids

We generate patient-derived brain organoids that faithfully recapitulate the neuro-immune interactions driving CNS disease — biology no animal model can replicate.

II

Multimodal Disease Signatures

We extract deep, multimodal readouts from our organoids — spanning transcriptomics, proteomics, and functional phenotypes — to build rich, disease-specific biological signatures.

III

Human Dataset Alignment

Our AI mines large-scale public human datasets to identify where organoid signatures map to real patient biology — anchoring our models in clinical reality from the start.

IV

Industry Data Partnerships

We partner with pharma and biotech to integrate proprietary clinical and trial datasets, continuously enriching our models and expanding their predictive power across indications.

V

Human CNS Foundation Model

Every dataset added makes the platform smarter — a compounding AI foundation model that gives pharma a human-grounded lens to predict drug response before entering the clinic.

Core thesis: Proprietary human biology, aligned to patient reality, and enriched by industry partnerships — a foundation model that gets more predictive with every dataset added.

Platform Impact

Team

We bring together neuroscience, AI, and translational thinking to build systems that bridge discovery and the clinic.

Renaud Schuck, PhD

Renaud Schuck, PhD

CEO — Neuroscience & AI

Jariel Bytheway, MBA

Jariel Bytheway, MBA

CBO — Strategy & Operations

Scientific Advisory Board

Our advisors ensure biological rigor, clinical relevance, and translational focus as we scale the platform.

Christopher Lovejoy

Christopher Lovejoy

Organoid Biology

Get in Touch

Interested in learning more about the platform or exploring a partnership? We'd love to hear from you.